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B6): This helps the brain create serotonin (which regulates mood) and norepinephrine (which helps the body cope with stress)

Dena Dubals lab at UCSF (Cell Reports, 2017) showed that peripheral klotho fragment administration enhanced cognition and neural resilience in young, aging, and -synuclein transgenic mice through NMDA receptor-dependent mechanisms

Vitamin B5 (Pantothenic Acid): Pantothenic acid is necessary for the synthesis of coenzyme A (CoA), which is involved in energy metabolism and the production of fatty acids, cholesterol, and certain hormones

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muciniphila increases the level of Akkermansia and decreases the relative abundance of Helicobacter , Lachnoclostridium , Candidatus_Saccharimonas , and Eubacterium_brachy , promoting the re-establishment of gut microbiota (Ding et al., 2021)