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Overexpression of adenosine A2A receptors in rats: effects on depression, locomotion, and anxiety

From one week to three months, there were significant increases in the levels of AcAc and HB (139.9 178.0 to 922.1 340.1 and 573.2 356.0 mol/L, respectively) and notable reductions in levels of both fasting blood sugar (96.8 11.5 to 91.2 13.0 mg/dL) and insulin (8.6 11.4 to 4.8 4.6 IU/mL)

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gondii show complex response, including reactive remodelling, secretion of interleukins that reduce parasite burden 241,242 and start to produce and release kynurenic acid, which is as an endogenous antagonist of NMDA and acetylcholine receptors