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These preliminary findings hold profound implications for clinical practice, potentially redefining therapeutic targets and timelines

This is shown in UVM Selfcare (2025): "Approximately 80% of weight loss comes from dietary changes." Therefore, small, repeatable eating habits matter more than short-lived extremes

The main outcomes were time to the first occurrence of HF composite outcome by HF status at baseline

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doi: 10.1016/j.nutres.2018.07.011, 18

The FDA has not approved metformin as a weight loss medication as its weight loss effect is inconsistent