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This matters a lot because a lot of actives (like vitamin C) needs a specific pH to work well and feel comfortable on skin

Barker JE, Bolafiosb JP, Land JM, Clark JB

That's where the "Ozempic-adjacent" framing comes from

Available at: FDA Advisory Committee Calendar Food and Drug Administration (2026) Bulk Drug Substances Used in Compounding Under Section 503A of the Federal Food, Drug, and Cosmetic Act

Cardiovascular disease and diabetes in people with severe mental illness position statement from the European Psychiatric Association (EPA), supported by the European Association for the Study of Diabetes (EASD) and the European Society of Cardiology (ESC)

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