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[6] The Yasko protocol views methylation cycle support as a six-step process: Regulate glutamate and GABA Since a high glutamate: GABA ratio can be hyperexcitatory, this is the number one priority in Yasko's version of the protocol

For health plans including these drugs on their prescription drug formularies, utilization management tools, like prior authorization and step therapy, can be used to allow medically indicated access to the drugs while controlling costs by tying coverage of the drugs to specific clinical and treatment criteria

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