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These are transient and manageable, but only if the clinician knows how to modulate the drip rate in real time based on patient feedback

10 Systemic agents including anti-epileptic, antimalarial, antipsychotic and cytotoxic/antineoplastic medications have been reported to potentially induce hyperpigmentation

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However, for seniors, the dosage may vary depending on their health status and the form in which they take the vitamin

Clin Dermatol 27(5):435445 Miyake M, Yamamoto S, Sano O, Fujii M, Kohno K, Ushio S, Iwaki K, Fukuda S (2010) Inhibitory effects of 2-Amino-3 H-phenoxazin-3-one on the melanogenesis of murine B16 melanoma cell line