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GLP-1 inhibitor drugs, originally developed for managing type 2 diabetes, mimic hormones that regulate blood sugar levels, which can help decrease appetite and lower calorie intake

Only lyophilized (powder) peptides tolerate freezing in published stability data reconstituted vials are refrigerated, not frozen

Semaglutide had been at steady state (100% of its full effect)

PMID: 41616957

Treatment should only continue if there is a reduction in HbA1c of at least 11 mmol/mol (1.0%) and weight loss of at least 3% of initial body weight after 6 months

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