Mechanism of Action 5-Amino-1MQ exerts its metabolic effects primarily through competitive inhibition of nicotinamide N-methyltransferase (NNMT), an enzyme belonging to the methyltransferase superfamily that is expressed in multiple tissues including liver, adipose tissue, skeletal muscle, kidney, and brain, with particularly high expression in visceral (abdominal) adipose tissue - the fat depot most strongly associated with metabolic disease
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Clinical Benefits: Supports red blood cell formation and helps prevent megaloblastic anaemia Essential for neurological function and nerve tissue health Plays a key role in DNA synthesis and cell metabolism Supports cognitive function, concentration, and mood regulation Assists in the conversion of homocysteine, supporting cardiovascular health Helps address fatigue and weakness associated with B12 deficiency For patients presenting with deficiency, a loading protocol is typically recommended: weekly injections for three weeks, followed by monthly injections for three months, then a maintenance injection every three months
It is known to be excreted in human milk
Inositol is a member of the B-Complex vitamin group and is a lipotropic agent
Sepsis happens when an infection you already have triggers a chain reaction throughout your body