The BPRF can be interpreted as indicating that, even accounting for between-study heterogeneity and its uncertainty, the log(RR) across the studied smoking range is at least as high as the BPRF (or at least as low as the BPRF for a protective risk)
Borrelli and OConnor wrote
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A person can then legally obtain a prescription for liquid nicotine or get a permit from the the Therapeutic Goods Administration to import a personal supply, however most users obtain the highly addictive substance illegally
The smoking comparison also has the potential to add to the burden of people who feel lonely and exacerbate the stigma associated with loneliness
McGarry Houghton, testified in front of the Washington state senates Health & Long-Term Care Committee about the science of vaping risks