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Free forms of glutamate have the ability to stimulate neurons on the tongue and are often added as flavor-enhancing food additives

A multidisciplinary expert consensus published in 2022 suggested pausing or reducing the dose of metformin therapy during initiation of a GLP-1 RA as an option to reduce GI side effects (Gorgojo-Martnez et al, 2022), although this is not widely practised in the UK

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When you have the correct amount, pull the needle out of the vial