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Availability depends on location, regulation, and distribution channel

Exemption from state tobacco excise taxes and the ability to offer a wide range of in-store and online promotions and discounts helps to keep the price of these oral nicotine products low for consumers

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some note improved smoothness after production moved to Greensboro, NC

However, there is some evidence that synthetic nicotine is more readily absorbed by the body than tobacco-based nicotine and therefore could be more addictive

Furthermore, the use of electronic cigarettes among youth could increase the risk of becoming long-term smokers of tobacco