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After two weeks of carnitine supplementation, no differences were found in healthy, active men during a time trial test

At the interventional level, combination therapy strategiesborrowed from cancer researchshould be employed, together with targeted drug delivery systems such as modified nanocarriers to expand the therapeutic window

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Importantly, a randomized controlled trial demonstrated that L-carnitine supplementation reduces the intramyocellular-to-extramyocellular lipid ratio in NAFLD patients, suggesting enhanced clearance and utilization of intracellular lipid stores in skeletal muscle independent of weight changes (41)

Chronic lithium treatment decreases brain phospholipase A2 activity Neurochem Res 1998