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"The positive ACHIEVE-1 results position orforglipron as a potential treatment option with meaningful A1C and weight reduction, and a safety profile similar to injectable GLP-1 therapies." Lilly and others are trying to develop oral therapies to complement current blockbuster drugs Novo Nordisk's Ozempic (semaglutide) and Lilly's dual GIP/GLP-1 agonist Mounjaro (tirzepatide) which are given by weekly injection to treat type 2 diabetes

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GLP-1 (glucagon-like peptide-1) medications are a class of drugs originally developed to treat type 2 diabetes

This increased risk has led researchers and regulators to urge caution for patients with existing eye disease

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Inhibition of DNA methylation in proliferating human lymphoma cells by immune cell oxidants