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Compared to M2-type macrophages, M1-type macrophages exhibit elevated expression of hepcidin antimicrobial peptide (Hamp), ferritin heavy chain (FTH), and ferritin light chain (FTL), with reduced levels of FPN and iron regulatory proteins 1/2 (IRP1/2), demonstrating enhanced iron storage capacity (96)
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Treatment plan: Specific goals (target ALT reduction, liver fat reduction percentage, fibrosis stage improvement) and timeline for reassessment (typically 6-12 months)
Tinahones, [email protected] This article was submitted to Clinical Diabetes, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers