Another recent study in Frontiers in Neuroscience hinted that GLP-1s might address chronic low-grade inflammation, a dominant feature in aging, by providing better balance in the metabolism of energy at the cellular level
The same paper also included a nested case-control component of 120,054 patients with T2DM followed for 7.4 years and observed a lower association between dementia and exposure to GLP-1RAs compared with other antidiabetics 39
Liraglutide improved GLUT1 and GLUT4 levels in the brain of 3xtg AD mice, a transgenic mouse model of AD [120]
It's worth noting that erectile dysfunction can be an early marker of cardiovascular disease and merits appropriate cardiovascular risk assessment
[DOI] [PubMed] [Google Scholar] 324.Moses RG, Kalra S, Brook D, et al
When caloric intake drops significantly, the resulting energy deficit can manifest as fatigue, weakness, or reduced exercise tolerance