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How GLP-1 Receptor Agonists Work in PCOS GLP-1 receptor agonists are medications that mimic a natural hormone (GLP-1) to help manage PCOS symptoms

These changes help reduce the risk of complications associated with obesity and metabolic disease

SURPASS-2 compared tirzepatide with semaglutide 1 mg in type 2 diabetes and showed larger mean weight reduction with tirzepatide in that trial, though weight-management trials used different endpoints

The absorption of semaglutide is mainly due to the indirect effect of SNAC

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