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doi:10.3390/jcm12010145 6

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If response is inadequate after the FDA-recommended evaluation period at therapeutic doses, consider switching to an alternative agent or referring for surgical revision evaluation in appropriate candidates

The next, phase 1b clinical trial in adults with T2DM compared once weekly retatrutide (0.5, 1.5, 3, 3 mg starting dose increased to 6, 3 mg starting dose increased to 12 mg) versus placebo versus dulaglutide 1.5 mg over 12 weeks [63]