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The most substantial evidence comes from a 2010 randomized controlled trial involving 40 healthy adults who received intravenous doses ranging from 42 to 1,260 mg of thymosin beta 4

Unlike medications that rely on ongoing dosing, bariatric surgery offers a one-time intervention with sustained weight loss results

Patients should receive comprehensive counseling about realistic expectations, potential side effects, the importance of continued lifestyle modification, and the need for ongoing nutritional monitoring

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