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Nature 541 , 321330 (2017)

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tolerance is significantly reduced on semaglutide Skipping meals causes fatigue, dizziness, and worsens cravings later Large portions triggers nausea within 3060 minutes Lying down after eating worsens reflux significantly Inadequate hydration worsens nausea, constipation, fatigue, and headache Rapid dose escalation discuss with your prescriber if symptoms are severe When Side Effects Mean You Should Stop and Call Your Doctor Most side effects are tolerable and resolve

Gupta T, Rathi S, Dhiman RK

Until recently, all actives were tested on the mushroom enzyme, but the human enzyme is of course much more complex