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Design and evaluation of peptide dual-agonists of GLP-1 and NPY2 receptors for glucoregulation and weight loss with mitigated nausea and emesis

Gastric point of care ultrasound (POCUS) features prominently in these recommendations as an objective tool

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Shift to fatty substrate utilization in response to sodium-glucose cotransporter 2 inhibition in subjects without diabetes and patients with type 2 diabetes

phase 3 signaled ~15% weight loss at top dose in obesity

These studies look at how it affects people over time, showing possible risks and benefits for managing type 2 diabetes and supporting weight loss