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Early animal and small human studies suggest it is generally well tolerated in the short term, but we do not yet have large, longterm trials
Running it simultaneously with other peptides conflicts with its design as a focused, short-cycle intervention
Carbohydrate timing around IGF-1 administration helps manage blood sugar
Accelerates preservative volatilization and introduces condensation that increases contamination risk
To maximize performance-enhancing effects in test subjects, researchers may prefer to administer IGF-1 LR3 to test subjects only on days when exercise is induced
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