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However, a comparative prospective randomized study found that the time needed to normalize PRL levels and tumor shrinkage by 50% was comparable with intensive DA treatment to standard dosage schedule (184)

To make thin OP50 plates, 0.05 mL overnight OP50 culture was applied and spread onto NGM plates (60 mm)

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However, tumor cells can develop resistance to PARP1 inhibition, and further studies are needed to understand this mechanism