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By comparison, Thorne offers a shorter 60-day window, making Wholesome Story the more flexible option for longer-term evaluation

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For instance, Bifidobacterium bifidum , a potent immunomodulator in human diseases, induces the production of regulatory T cells (Verma et al., 2018), regulates helper T cell 2 and Th17-mediated immune responses in the intestine, inhibits the production of pro-inflammatory cytokines such as TNF-, IL-6, IL-1, IL-18, IL-22, and IL-9, while promots the expression of anti-inflammatory cytokines such as IL-10, IL-4, and IL-5 ( Faecalibacterium prausnitzii, Clostridium, Eubacterium rectale , and Roseburia demonstrate pronounced enrichment under these conditions