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Implications for Clinical Practice Our findings suggest that integrating hormonal surveillance with individualized pharmacotherapy may enhance long-term care of adolescents post-LSG, but further research is required to establish the utility and cost-effectiveness of such strategies

Importantly, the researchers arent calling for everyone to dump out their GLP-1s over their findings

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This complementary relationship suggests that adequate levels of both compounds may provide synergistic immune support benefits

3 Thyroidbrain axis pathophysiology and neurological manifestations The major mechanistic routes linking thyroid dysfunction to neuropsychiatric manifestations are summarized in Figure 2, highlighting disrupted hormone transport/activation in the brain, neurotransmitter imbalance, oxidative stressneuroinflammation, and bloodbrain barrier vulnerability