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Oxidation in small-molecule drugs often involves free radical-mediated autocatalytic reaction initiated by the abstraction of hydrogen from the carbon next to a heteroatom, followed by reaction with oxygen to form a peroxide free radical

However, it's worth noting that the studies reviewed were observational, and further research is needed to establish a definitive causal link

However, the prescribing information for Wegovy (another semaglutide product) does have a warning about avoiding use of the drug in people with a history of suicidal thoughts or behaviors

Exploring Compounded Semaglutide and Tirzepatide Solutions During a drug shortage, pharmacies are allowed to offer compounded medications which refer to customized formulations of a drug that are prepared by a certified compounding pharmacy