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Selenoprotein deficiency and high levels of selenium compounds can effectively inhibit hepatocarcinogenesis in transgenic mice

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297,307 In addition, astrocytes lose AQP4 channels in their endfeet and down-regulate expression of glutamate transporters, thus adding to excitotoxic damage of oligodendrocytes

Changes might include eating smaller meals and limiting high-sugar foods

The tool consists of 10 questions to assess bias based on the study design, the number of animals, the type of control, blinding, and randomization of the process, the analysis of the results, and the quality of outcome assessment, among others