FDA Status: What You Should Know BPC-157 is not FDA-approved to treat any medical condition
Gastric stasis in migraine: more than just a paroxysmal abnormality during a migraine attack

Specific situations requiring medical review include: Severe or persistent gastrointestinal side effects from Mounjaro that significantly limit your food intake for more than a few days You are taking metformin in addition to Mounjaro, as this combination increases B12 deficiency risk You have a history of pernicious anaemia, gastric surgery, or conditions affecting nutrient absorption You are considering stopping B12 injections whilst taking Mounjaro You experience any unexplained neurological symptoms Urgent medical attention is needed if you develop severe, persistent abdominal pain (which may radiate to the back), persistent vomiting, fever, or yellowing of the skin/eyes, as these could indicate pancreatitis or gallbladder problems Your GP or practice nurse can arrange blood tests to check your B12 levels (serum B12, holotranscobalamin, and if borderline, methylmalonic acid levels may be used where available) and determine the appropriate frequency of B12 injections if deficiency is confirmed

While this represents a higher per-treatment cost than oral supplements, the superior absorption and reduced frequency often make injections cost-competitive over time, particularly for those who dont absorb oral forms effectively
The combination can produce balance-effects
This approach identifies people who actually need it while avoiding unnecessary supplements and costs for others