To test whether ATP released from GLP-secreting cells is sufficient to activate ND neurons, we co-cultured EYFP-labelled ND neurons (derived from NeuroD1-Cre/Rosa26-EYFP mice), together with Gq-DREADD-mCherry-transfected GLUTag cells (Fig
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This approach lacks robust clinical trial data but has theoretical appeal for cost management and side effect reduction
And as weve discussed, glutathione deficiency can lead to oxidative stress