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Future research should focus on strategies to enhance its bioavailability and on conducting large-scale randomized controlled trials to more comprehensively assess its efficacy and safety in the treatment of AP

Vitamin B12 deficiency can cause symptoms such as fatigue, weakness, numbness or tingling in the hands and feet, balance problems, and memory difficulties

"Physicians should have every available arrow in the quiver to treat illness and, because of the FDA's inaction, they don't," said Lee Rosebush, who helped bring the lawsuit against FDA and represents a group of large compounding pharmacies

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Footnotes Disclosure: The authors declare no conflict of interest Reference List 1.Weindruch R