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Eur J Rheumatol Inflamm

The problem is that this substance decreases in our bodies over time

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Additionally, the role of non-classical ferroptosis regulators (e.g., FSP1, DHODH, and GCH1/BH4) in LN is entirely unexploredwhether these radical-trapping antioxidant pathways compensate for GPX4 deficiency in immune cells or renal tissue, or if their dysfunction exacerbates ferroptosis susceptibility, has not been investigated