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Additionally, caffeine is a diuretic, so you must drink extra water to compensate and prevent dehydration

doi:10.1016/j.cmet.2013.04.008 24

X., Aguiaga, S., Vsquez, P

These discrepancies can be attributed to the genetic variation among different ethnic backgrounds in fatty acid metabolism plus the complexity of PUFA metabolism (133)

However, both medications share similar side effect profiles, and most effects are manageable and improve over time as your body adjusts to the medication