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The Lancet Rheumatology , 2026

2022 Oct;21(10):49904998

Future studies with larger cell sizes should be conducted to compare sub-groups patients with different symptom profiles

Conditions such as pernicious anemia, which affects the absorption of B12, may also warrant coverage, as well as certain chemotherapy treatments that necessitate B12 supplementation

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Overall, L-GSH supplementation for 3-months in individuals with T2DM decreased levels of the proinflammatory cytokine IL-6, while the placebo group had a significant increase in IL-6 levels