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Briefly, HCT116 cells transfected with the cDNA of Venus (1 10 6 cells/mice), a highly sensitive fluorescent protein on tissue slice sections, 66 were transplanted into the spleens of 10-week-old male NOG mice

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For behavioral studies, data were analyzed by ANCOVA, or repeated-measures one-way or two-way ANOVA followed by Tukeys or Bonferronis post hoc test as appropriate