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It also has a direct effect on the heart and endothelial cells, preventing the progression of atherosclerosis through mechanisms such as increasing nitric oxide and decreasing endothelin-1, reactive oxygen species, and inflammatory cytokines

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189 NogueiraAMBarbosaAJ

doi: 10.1016/j.smrv.2016.02.001

Anyone with a diagnosed gut condition, including inflammatory bowel disease, should consult a gastroenterologist before starting a supplement that actively modifies the gut microbiome

Because it is administered via a weekly subcutaneous injection, the medication enters the bloodstream relatively quickly