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As of now, there is no conclusive evidence establishing a direct link between the medication and the condition

To simulate the prescribed human dosage (200 mg per day), an equivalent hamster dose of 25 mg per kg per day was converted on the basis of body surface area

MIN6 cells were pretreated with 1 mM metformin for 2 h (thin dotted line of left panel) or simultaneously with 10 nM GLP-1 (thick dotted line of left panel)

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Furthermore we suggest to update earlier studies by publishing follow-up data on neonatal outcome multiple years after maternal exposure