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Neurological symptoms can be subtle for a long time
It salvages tissue viability by maintaining ATP levels during critical stress
Studies of physical activity in dogs have associated regular exercise with several positive health outcomes, including maintenance of healthy weight and lean body mass, increased energy expenditure, improved glucose metabolism, and strengthening of the human-animal bond
Key areas of investigation include modulation of the nitric oxide (NO) system through interaction with NOS isoforms, upregulation of growth factor receptors (including VEGFR2 and EGF receptor systems), and engagement of the FAK-paxillin signaling cascade associated with cell migration and adhesion
Some patients may notice changes in sleep, recovery, or energy earlier, while changes in body composition, skin quality, or wellness goals may take longer
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