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Energy metabolism imbalance directly or indirectly by the gut microbiota and its metabolic products is involved in the occurrence and development of obesity (Figure 1)

Tph1 is mainly expressed in enterochromaffin cells of the gut epithelium, whereas Tph2 is mainly produced in serotonergic neurons of the central and enteric nervous systems (Walther et al., 2003)

doi: 10.1016/j.jfca.2018.01.006 222 RastogiA.ShuklaS

Weight Loss Beyond diabetes management, tirzepatide is also effective for weight loss

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