what happens if glp 1 isn t refrigerated Taking a GLP-1? Doctors say not to forget about movement and mental health Ozempic and Refrigeration: How Long

In terms of goals, weight loss mattered, but the chance to protect my heart and kidneys came to matter more

Etiology Genetics COL5A1 or COL5A2 mutation in 40-50% less common mutations identified below Associated conditions Connective tissue disorder characterized by Classification Berlin Classification (1988) - revised Types I - XI exist Villefranche Classification (1998) Presentation Symptoms double-jointedness easily damaged, bruised, & stretchy skin easy scarring & poor wound healing increased joint mobility, joint popping, early arthritis chronic musculoskeletal pain (50%) Physical exam a score of 5 or more on 9-point Beighton-Horan scale defines joint hypermobility

Mulherin DM, Thurnham DI, Situnayake RD

Studies ongoing in NASH/MASH (liver disease)

If the endpoint was reached, mice were terminated by cervical dislocation or CO 2 gas chamber

Tingling, numbness, or prickling have been reported in retatrutide trials and appear to increase at higher doses