In a rabbit model of osteoarthritis, intra-articular injection of AOD-9604 combined with hyaluronic acid (HA) demonstrated improvements in cartilage morphology and joint surface integrity
Vitamin C is a critical cofactor for collagen synthesis
Contraindications/Precautions: Who should not take this medication? Patients with early hereditary optic nerve atrophy, cyanocobalmin hypersensitivity, and those who are pregnant
The recommended daily intake of Vitamin B12 varies by age and health status: Birth to 6 months Infants 712 months Children 13 years Children 48 years Children 913 years Teens 1418 years Adults Pregnant teens and women Breastfeeding teens and women Vitamin D3 and B12 can be taken together safely, as they do not interact negatively and support overall health
Vitamin B12 is generally very safe even at high doses because it is water-soluble and excess amounts are excreted in urine
It is not intended for diagnostic, therapeutic, or clinical applications