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Elevated IOP has been shown to upregulate interleukin-1 (IL-1), suggeting that astrocytes and Mller cells may initiate this inflammatory cascade, leading to microglial activation and subsequent neuronal injury (147, 148)

The Role of Vitamin C and Co-Factors Antioxidants rarely work alone

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10.1016/s1875-5364(18)30116-x 68 HirataN.NarutoS.OhguchiK.AkaoY.NozawaY.IinumaM.et al (2007)