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Evidence that intestinal glucagonlike peptide-1 plays a physiological role in satiety

Abstract Background With the prevalence of obesity rising in the US, medical management is of increasing importance

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Phase 3 data from the ATTAIN-1 trial, which evaluated 3,127 adults with obesity over 72 weeks, showed a mean weight loss of 11.2%, with more than half of participants achieving at least 10% body weight reduction