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However, it is rapidly degraded by dipeptidyl peptidase-4 (DPP-IV) and other serum proteases, giving it a half-life of only 10-20 minutes

Studies conducted using the adiponectin knock-out (KO) murine model revealed that adiponectin KO mice exhibited a notably more severe form of colitis in comparison to their wild-type counterparts

15 The thyroid gland contains a higher concentration of selenium than any other organ, owing to the presence of selenoproteins, including glutathione peroxidase , which protects the gland from oxidative stress by utilizing glutathione to neutralize the hydrogen peroxide produced during thyroid hormone synthesis

We review studies revealing the neuroprotective actions of GLP-1 analogues in pre-clinical models of AD and PD and promising results from recent clinical trials

doi:10.1016/s0140-6736(11)61454-2