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Extensive lung transcriptome analysis established that individuals with high risk factors for severe disease outcomes expressed ACE2 at much greater levels than control subjects 19

Despite promising preclinical data, clinical trials in humans are extremely limited, and the compound remains largely experimental, with ongoing research required to fully characterize pharmacokinetics, optimal dosing, long-term safety, and potential off-target effects

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Compounded products may have additional pharmacy-specific quality and sterility considerations verifying that the dispensing pharmacy is state-licensed, USP compliant for sterile compounds, and that the prescribing provider conducts a clinical evaluation are critical

To switch between mcg and mL, know the solutions concentration