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A 5mg semaglutide vial is typically reconstituted with 1 to 2ml of bacteriostatic water , producing concentrations of 5mg/ml or 2.5mg/ml respectively

They were originally designed for folks with Type 2 Diabetes for the purpose of blood sugar regulation

However, the relatively small differences with exendin-asp3 suggest that additional mechanisms beyond receptor trafficking may be involved in the blunted insulin secretory response with this compound

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This is thought to be due to differences in how the medication is absorbed into the bloodstream from different types of tissue