In addition, lower levels of folate in the brain are associated with higher blocking FRAA titers
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Also, n-3 lowers the increased caspase-3 and calpain activity detected by p-nitroanilin absorbance and calcium- and non-calcium-dependent fluorescence in ethanol conditions, reducing cell injury, neurodegeneration, brain hemorrhage, congestion, necrosis, leukocytosis and microglia activation (43)
This vulnerability is primarily due to the high content of PUFAs in their membranes, the limited availability of antioxidant enzymes, and the lack of effective DNA repair mechanisms
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