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In many cases, a faecal immunochemical test (FIT) may be performed in primary care as part of the assessment pathway, in line with NICE guideline NG12

However, Orlistat can still achieve modest weight loss when combined with perfect dietary compliance studies show that 60% of people taking Orlistat lost at least 5% of their body weight after 6 months

(PubMed) Jacob S, Rett K, Henriksen EJ, Haring HU

But, some see better results by stepping up to 1.7 mg and eventually 2.4 mg weekly

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Niacin is a vitamin, and your body needs a certain amount of it but too much, like in the form of over-the-counter supplements, can have negative effects