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10.1210/jc.2018-00004 30 GolembiewskaE.SafranowK.Kabat-KoperskaJ.MyslakM.CiechanowskiK

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The sample comprised 353,153 veterans 18 or older

The relatively high prevalence of C316N in our patients is in line with previous reports showing a prevalence of C316N ranging from 11% to 40% in patients with GT1b enrolled in clinical trials, and this mutation was more frequent among European subjects than among those from the United States 87,88

In contrast, dietary d-carnitine intake reduced the acyl-carnitine concentration in the body and induced lipid accumulation in the liver, which was accompanied by lipotoxicity

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