Replacement is also important
Even though meta-analyses found no psychiatric side-effects, such as depression and bad mood, derived from smoking cessation 47,48 among general smoking quitters, some studies have detected an increased depression risk among those who attempt to quit unsuccessfully 49 and somatic adverse reactions among individuals with nicotine replacement therapy 50
According to Ivan Berlin, toxicologist in Paris and Lausanne and an internationally renowned expert in this area, a single higher dose of nicotine increases addiction: When we talk of greater dependence, were talking about the difficulty of saying no, and thus greater toxicity, Jacques Cornuz, director of the outpatient clinic at the University of Lausanne, who is an epidemiologist and tobacco specialist who led the Federal Commission for the Prevention of Smoking (CFPT) from 2007 to 2014
Lee S, Kang S, Joo YS, Lee C, Nam KH, Yun HR, Park JT, Chang TI, Yoo TH, Kim SW, Oh KH, Kim YH, Park SK, Kang SW, Choi KH, Ahn C, Han SH (2021) Smoking, smoking cessation, and progression of chronic kidney disease: results from KNOW-CKD study
That, too, is unclear
The American Association of Poison Control Centers and other health experts recommend wearing gloves or using other protective materials when handling e-cigarettes