Metformin has long been associated with cardiovascular benefits based on the UKPDS trial data and observational studies, suggesting a 10-15% reduction in cardiovascular events
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Microbiome Modulation: Recent research demonstrates SBI partially resists digestion, reaching the colon where it specifically stimulates the production of health-promoting metabolites including indole-3-propionic acid (IPA) a tryptophan metabolite associated with gut barrier integrity and systemic health alongside increases in short-chain fatty acids.*
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doi:10.1074/jbc.M109.030130 Di Tucci C, Galati G, Mattei G, et al