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reported that the combination of dexamethasone (DEX) and artesunate (ART) can be used to treat RA by regulating the HIF-1/NF-B signaling pathway, controlling ROS clearance, and reversing macrophage polarization (141)

For example, antioxidant and cytoprotective effects of DADS against acute ethanol-induced liver damage in mice were associated with the ability to trigger Nrf2-dependent HO-1 activation (22)

2007;292:C175967

Research shows enhanced granulation tissue formation, improved re-epithelialization, increased collagen deposition, and superior dermal remodeling through VEGF pathway activation

Visit 8 was performed as stated previously for visit 2

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